5/29/2023 0 Comments Rj yeatmanIn this study, we have explored an assumption in which there exists a shift in playing strategy of enzymes from normal to a different biological condition (here cancer) by investigation of pattern alterations in the metabolic subsystem of four cancer cell types (in four cancer stages) using flux calculations and Gene Ontology analysis. Such enzymes behaviors are very similar to a competitive game where different players try to play for reaching a specific outcome, either by a cooperative or selfish strategy. So, it is reasonable to find metabolism variations within a cell in different conditions. Besides, every change in a biological system and its environment within a cell could lead to metabolism alterations due to natural cell response. In metabolism processes, enzymes are involved in a cooperative manner of step by step mechanisms trying to guarantee cell survival.
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